It is present in more than half of patients allergic to perennial allergens (mites or cat hair). Some epidemiological studies show that more than 70 percent of patients with allergic rhinitis have pronounced eye disorders, and that patient population has a more impaired quality of life than those with only nasal symptoms.
Various therapeutic modalities are used for the purpose of preserving or strengthening the epithelial barrier. Recently, solutions containing ectoin have been used for this purpose. Ectoin is a bacterial peptide that prevents epithelial barrier lesions by osmotic stress and is therefore used in the prevention and treatment of not only respiratory, but also skin, eye and digestive manifestations of epithelial barrier lesions.